Table 3.

Tertiles of HOMA-IR and Matsuda Index at study entry predict the risk of developing Stage 3 type 1 diabetes

	HOMA-IR n=6114			Matsuda Index n=6256
Parameter	Parameter estimate	p value	HR	Parameter estimate	p value	HR
T2 vs T1	−0.256	0.0002	0.774	0.173	0.0249	1.190
T3 vs T1	−0.406	<0.0001	0.666	0.415	<0.0001	1.516
aT2 vs T1	0.270	0.0001	1.311	−0.538	<0.0001	0.583
aT3 vs T1	0.681	<0.0001	1.977	−0.783	<0.0001	0.457
Index60 (baseline)	1.196	<0.0001	3.307	1.208	<0.0001	3.349
bT2 vs T1	0.254	0.0002	1.289	−0.618	<0.0001	0.539
bT3 vs T1	0.670	<0.0001	1.954	−0.952	<0.0001	0.386
Index60 (baseline)	1.193	<0.0001	3.298	1.157	<0.0001	3.183
Age (baseline)	−0.022	<0.0001	0.978	−0.024	<0.0001	0.976

Cox regression analysis with baseline Index60, or Index60 and age, as covariates for adjustment

^aIndented rows under Parameter heading indicate adjustment for Index60

^bIndented rows under Parameter heading indicate adjustment for Index60 and age

Baseline: monitoring visit when the initial OGTT was performed