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. 2024 Jan 3;10(1):e200122. doi: 10.1212/NXG.0000000000200122

Figure 2. Muscle Histopathology of Patient-III.

Figure 2

(A) Hematoxylin and eosin—fiber size variability, internally placed nuclei, and fiber splitting (×400). (B) ATPase pH 9.4—type 2 predominance (×200). (C) Modified Gomori trichrome—inflammatory foci and rimmed vacuoles (yellow arrow) (×400). (D) Electron microscopy—varying degrees of disorganization of myofibrils with loss of their normal striation pattern and nemaline rods (X 37,500) (orange arrow).