Table 2.
Coronary Physiology and Exercise Electrocardiographic Stress Test Parameters
| Ischemic Group (n = 32) | Nonischemic Group (n = 70) | P Value | |
|---|---|---|---|
| Coronary anatomy and physiology | |||
| Diameter stenosis | 0.128 | ||
| <30% | 28 (88) | 67 (96) | |
| 30%-50% | 4 (12) | 3 (4) | |
| Pd/Pa | 0.95 ± 0.03 | 0.95 ± 0.03 | 0.807 |
| FFR | 0.90 ± 0.06 | 0.90 ± 0.04 | 0.971 |
| CFR | 2.3 (2.0-2.9) | 2.6 (2.0-2.9) | 0.507 |
| hMR, mm Hg/cm/s | 2.0 ± 0.8 | 2.1 ± 0.7 | 0.372 |
| AChFR | 1.2 ± 0.3 | 1.5 ± 0.6 | <0.001 |
| Endothelium-independent microvascular dysfunction (CFR <2.5) | 20 (63) | 30 (43) | 0.066 |
| Endothelium-dependent microvascular dysfunction (AChFR ≤1.5) | 31 (97) | 39 (56) | <0.001 |
| CMD | 32 (100) | 46 (66) | <0.001 |
| Exercise stress testing | |||
| Exercise time, s | 348 ± 164 | 342 ± 164 | 0.860 |
| Presence of angina during EST | 25 (78) | 42 (60) | 0.074 |
| Peak heart rate, beats/min | 145 ± 15 | 136 ± 23 | 0.035 |
| Peak systolic blood pressure, mm Hg | 191 ± 26 | 180 ± 34 | 0.137 |
| Peak rate-pressure product, mm Hg × beats/min | 27,662 ± 4,846 | 24,678 ± 7,130 | 0.039 |
Values are n (%), mean ± SD, or median (Q1-Q3).
AChFR = acetylcholine flow reserve; CFR = coronary flow reserve; CMD = coronary microvascular dysfunction; EST = exercise electrocardiographic stress testing; FFR = fractional flow reserve; hMR = hyperemic microvascular resistance.