Table.

Predictive values of whole-genome sequencing antibiotic resistance prediction with respect to standard pDST

	Resistant cases according to pDST	Sensitivity	Specificity	Negative predictive value	Positive predictive value	Accuracy
Isoniazid	41	85·4% (70·8–94·4)	99·8% (99·2–100·0)	99·1% (98·1–99·6)	97·2% (83·1–99·6)	99·0% (97·9–99·6)
Rifampicin	15	73·3% (44·9–92·2)	99·6% (98·6–99·9)	99·4% (98·6–99·7)	78·6% (53·2–92·2)	98·9% (97·8–99·6)
Ethambutol	12	50·0% (21·1–78·9)	99·6% (98·7–99·9)	99·1% (98·5–99·5)	66·7% (36·1–87·6)	98·7% (97·5–99·4)
Pyrazinamide	21	57·1% (34·0–78·2)	100·0% (99·4–100·0)	98·7% (97·9–99·2)	100·0% (73·5–100·0)	98·7% (97·5–99·4)

Data are n or % (95% CI). pDST=phenotypic drug susceptibility testing.