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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Obesity (Silver Spring). 2023 May 25;31(7):1825–1843. doi: 10.1002/oby.23774

FIGURE 6.

FIGURE 6

Pair feeding RAGE229–150 ppm diet to obese mice undergoing diet-induced weight loss increases thermogenesis. (A) Experimental schematic of pair-feeding mice switched from HFD to RAGE229–150 ppm or base diet. (B) Change in daily rectal temperature measured over the indicated time course after diet switch in pair-fed mice (n = 5 per group). (C) Change in body mass measured over the indicated time course after diet switch in pair-fed mice (n = 5 per group). Linear mixed-effect model was adopted for correlated/time-series data, with post hoc t test for group comparisons at each time point. For change in body mass in pair-fed mice (panel C), one tailed t test was used to compare groups at each time point. HFD, high-fat diet; RAGE229, receptor for advanced glycation end products. *p < 0.05; **p < 0.01; ***p < 0.001 [Color figure can be viewed at wileyonlinelibrary.com]