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. 2024 Jan 16;12:3. doi: 10.1186/s40560-023-00714-y

Table 3.

LLST and AD characteristics depending on timing of LLST

Early LLST Late LLST p
118 (35.2) 217 (64.8)
Degree (withdraw vs. withhold)
 Withdraw 36 (30.5) 134 (61.8) < 0.001
Reason
 Patients wish* 66 (55.9) 37 (17.1) < 0.001
 SDMs wish* 13 (11.0) 58 (26.7)
 Medical reason* 39 (33.1) 122 (56.2)
ICU mortality 27 (22.9) 94 (43.3) < 0.001
In hospital mortality 48 (40.7) 180 (82.9) < 0.001
Advance directive
 Present 64 (54.2) 69 (31.8) < 0.001
Cardiopulmonary resuscitation
 Allow 4 (3.4) 12 (5.5) 0.013
 Refuse 44 (37.3) 29 (13.4)
Intubation
 Allow 4 (3.4) 18 (8.3) 0.001
 Refuse 32 (27.1) 21 (9.7)
ICU care
 Allow 5 (4.2) 15 (6.9) 0.020
 Refuse 17 (14.4) 12 (5.5)
Artificial feeding
 Allow 15 (12.7) 14 (6.5) 1.000
 Refuse 24 (20.3) 22 (10.1)
LST
 Allow 6 (5.1) 16 (7.4) 0.043
 Refuse 53 (44.9) 51 (23.5)
Number of EOL talks (median [IQR]) 1 [0, 2] 3 [2, 5] < 0.001
Sex physician
 Female 36 (30.5) 93 (42.9) 0.314

Data shown as n (%) unless otherwise stated. LLST Limitation of Life Sustaining Treatments, SDM surrogate decision maker, ICU Intensive Care Unit, LST Life Sustaining Treatment, EOL End of Life, IQR Inter Quartile Range. Subgroups marked with * were significant in the post-hoc subgroup analysis