Table 1.
Hemodynamic and neuromonitoring data before and after passive leg raising
| Parameter | Baseline | PLR | p-value | rrb |
|---|---|---|---|---|
| ICP (mmHg) | 13.7 (8.3–16.4) | 15.4 (12.0–19.2) | < 0.001 | − 1.0 |
| MAP (mmHg) | 64.8 (64.0–66.6) | 71.5 (68.0–74.2) | < 0.001 | − 0.99 |
| CPP (mmHg) | 51.1 (47.4–55.6) | 56.4 (49.6–61.5) | < 0.001 | − 0.81 |
| PRx (a.u.) | 0.12 (0.01–0.24) | 0.43 (0.34–0.46) | < 0.001 | − 1.0 |
| SpO2 (%) | 99 (96–100) | 99 (96–100) | 0.916 | 0.03 |
| rSO2 (%) | 59 (56–68) | 61 (56–63) | 0.940 | 0.02 |
| O2Hbi (umol/L) | 1.8 (0.8–3.7) | 4.3 (2.5–5.6) | < 0.001 | − 0.96 |
| HHbi (umol/L) | 1.6 (0.2–2.9) | 2.7 (1.4–4.0) | 0.007 | − 0.64 |
| cHbi (umol/L) | 3.6 (1.9–5.3) | 7.8 (5.2–10.3) | < 0.001 | − 0.93 |
| PaO2 (%) | 101 (94–103) | 104 (97–111) | 0.041 | − 0.49 |
| PaCO2 (%) | 41 (38–43) | 41 (38–43) | 0.255 | − 0.31 |
Statistically significant results are reported in bold
PLR passive leg raising, ICP intracranial pressure, MAP mean arterial blood pressure, CPP cerebral perfusion pressure, PRx pressure reactivity index, SpO2 systemic oxygen saturation, rSO2 regional cerebral saturation, O2Hbi oxygenated hemoglobin, Hhbi deoxygenated hemoglobin, cHbi total hemoglobin, PaO2 partial pressure of O2, PaCO2 partial pressure of CO2; p-value was obtained using paired Wilcoxon signed-rank test and the effect size was assessed using the rank-biserial correlation (rrb) coefficient