TABLE 3.
Genomic characteristics of the bla KPC-2-bearing plasmids based on long-read sequencing
| Plasmid name | Size (kb) | Inc type and pMLST | bla KPC-2-harboring genetic elements | ARG-profile | Species | Genome accession no. |
|---|---|---|---|---|---|---|
| pCF13141-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | C. freundii | VKMY01000050 |
| pCF08698-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | C. freundii | VKMD01000077 |
| pCP13069-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | C. portucalensis | VKMZ01000118 |
| pCK13142-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | C. koseri | VKNB01000047 |
| pKP37361-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | K. pneumoniae | CP104944 |
| pEClo_Surv151-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | E. xiangfangensis | CP104949 |
| pKV30046-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | K. variicola | CP104940 |
| pCPsc18-2783-KPC2 | 78 | IncN[pMLST15] | NTEKPC-Y | A | C. portucalensis | CP104956 |
| pEC16155-KPC2 | 79 | IncN[pMLST15] | NTEKPC-Y | A | E. coli | VKML01000077 |
| pCA13304-KPC2 | 77 | IncN[pMLST15] | NTEKPC-Y | A | C. amalonaticus | VKME01000146 |
| pEXva18-1651-KPC2 | 79 | IncN[pMLST15] | NTEKPC-Y | A | E. xiangfangensis | CP104948 |
| pCK_Surv347-KPC2 | 79 | IncN[pMLST15] | NTEKPC-Y | A | C. koseri | CP104957 |
| pEC32446-KPC2 | 69 | IncN[pMLST15] | NTEKPC-Y | A a | E. coli | CP104950 |
| pEC14408-2-KPC2 | 88 | IncN[pMLST15] | NTEKPC-Y | A | E. coli | LT599827 |
| pCFur18-0060-KPC2 | 89 | IncN[pMLST15] | NTEKPC-Y | A | C. freundii | CP104958 |
| pCF37969-KPC2 | 89 | IncN[pMLST15] | NTEKPC-Y | A | C. freundii | CP104960 |
| pEC32009-KPC2 | 195 | IncN[pMLST15]:: IncF[F36 +31:A4:B10] | NTEKPC-Y | A | E. coli | CP104951 |
| pKV_Surv097-KPC2 | 217 | IncN[pMLST15]:: IncFII(K2:A-:B-]::IncR | NTEKPC-Y | A | K. variicola | CP104941 |
| pCF38954-KPC2 | 80 | IncN[pMLST15] | NTEKPC-Y | D | C. freundii | CP104959 |
| pCF_Surv457-KPC2 | 83 | IncN[pMLST15] | NTEKPC-Y | B a | C. freundii | CP104961 |
| pRP_Surv085-KPC2 | 73 | IncN[pMLST15] | NTEKPC-Y | B | R. planticola | CP104937 |
| pEC_Surv265-KPC2 | 69 | IncN[pMLST15] | NTEKPC-Y | D | E. coli | CP104953 |
| pKP38941-KPC2 | 69 | IncN[pMLST15] | NTEKPC-Y | C | K. pneumoniae | CP104943 |
| pKP41623-KPC2 | 164 | IncN[pMLST15]::IncFII[K9:A-:B-] | NTEKPC-Y | D | K. pneumoniae | CP104942 |
| pRO41724-KPC2 | 71 | IncN[pMLST15] | NTEKPC-Y | E | R. ornithinolytica | CP104938 |
| pKP_Surv398-KPC2 | 59 | IncN[pMLST15] | NTEKPC-Y | E | K. pneumoniae | CP104946 |
| pKP_Surv434-KPC2 | 59 | IncN[pMLST15] | NTEKPC-Y | E | K. pneumoniae | CP104945 |
| pKV33665-KPC2 | 59 | IncN[pMLST15] | NTEKPC-Y | E | K. variicola | CP104939 |
| pEC_Surv291-KPC2 | 59 | IncN[pMLST15] | NTEKPC-Y | E | E. coli | CP104952 |
| pCF12908-KPC2 | 59 | IncN[pMLST15] | NTEKPC-Y | E | C. freundii | VKMA01000036 |
| pEC_Surv190-KPC2-1 | 52 | IncN[pMLST15] | NTEKPC-Y | E | E. coli | CP104954 |
| pEC_Surv190-KPC2-2 | 23 | IncQ1-like | NTEKPC-Y | E b | E. coli | CP104955 |
| pEC11992-KPC2 | 48 | IncN[pMLST15]∆ | NTEKPC-Y | F | E. coli | VKMQ01000091 |
| pKA36387-KPC2 | 166 | IncF[Y2 a :A ~ 22:B-] | Other c | Other d | K. aerogenes | CP104947 |
| pKP11394-KPC2 | 241 | IncF[K2:A-:B-]::IncFIB(pQil) :IncFIB(pQil) | Tn4401a | Other e | K. pneumoniae | VKNL01000120 |
a
these both plasmids carried only one copy of sul1.
b
pEC_Surv190-KPC2-2 harbored an E-like profile without strA,, but sul2.
c
pKA36387-KPC2 harbored neither a NTEKPC-Y nor Tn4401.
d
bla KPC-2 and bla TEM-1 are not adjacent to each other.
e
pKP11394-KPC2 harbored two Tn4401a with bla KPC-2.