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. 2023 Dec 20;15(1):e03011-23. doi: 10.1128/mbio.03011-23

Fig 3.

Fig 3

Dexamethasone suppresses inflammatory pathways of KSHV-transformed cells. (A) PCA plot of mRNA-seq results of MM and KMM cells treated with 0.1 µM dexamethasone for 0, 2, and 4 days. (B) Volcano plots of DEGs in MM and KMM cells treated with dexamethasone described in panel A. Cutoffs: fold change > 2.5, FDR < 0.05, P < 0.05. (C) Venn diagrams showing overlaps of upregulated and downregulated DEGs of MM and KMM cells treated with dexamethasone. (D) Heatmaps of DEGs of MM and KMM cells treated with dexamethasone. (E) Bubble chart of enriched GOBP pathways in MM and KMM cells treated with dexamethasone. (F) Enrichment plots of inflammatory response (GSEA hallmark) and cell cycle (KEGG) of MM and KMM cells treated with dexamethasone.