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. 2024 Jan 3;67(1):E1–E6. doi: 10.1503/cjs.003722

Table 3.

Cost range for 90-day prescriptions, not including dispensing fee*

Drug class Generic Brand name


Cost rage, $ Cost variation, $ Cost range, $ Cost variation, $
Angiotensin-converting-enzyme inhibitors

 Enalapril 25.73–74.01 48.28 134.64–411.03 276.39

 Lisinopril 26.00–76.01 50.01 96.93–747.00 650.07

 Perindopril 27.52–52.01 24.49 89.01–363.39 274.38

 Ramipril 7.94–65.17 57.23 83.55–264.03 180.48

 Trandolapril 22.44–56.45 34.01 87.90–150.00 62.10

Angiotensin receptor blockers

 Candesartan 22.17–48.45 26.28 138.93–399.72 260.79

 Valsartan 15.54–61.01 45.47 125.79–452.70 326.91

Antiplatelet agents

 ASA 10.35–21.90 11.55 16.35–66.57 50.22

 Clopidogrel 25.57–59.41 33.84 271.74–384.03 112.29

Direct factor Xa inhibitor

 Rivaroxaban, 2.5 mg twice daily NA 129.15–174.66 45.51

Statins

 Atorvastatin 23.19–45.21 22.02 246.03–348.30 102.27

 Rosuvastatin 19.71–50.16 30.45 198.03–291.03 93.00

ASA = acetylsalicylic acid; NA = not applicable.

*

Cost represents that of the maximum evidence-based dosage of each drug, except that the enalapril dosage was 10 mg twice daily (the American College of Cardiology guideline’s maximum dosage is 20 mg twice daily, but only for patients categorized as New York Heart Association Functional Class IV12), and the rivaroxaban dosage was 2.5 mg twice daily, in keeping with the COMPASS regimen therapy.14