TABLE 1.
Occurrence of all amino acids in position 4 of the PEXEL in proteins predicted to be exported in the indicated exportomesa
| Category | Amino acid at fourth position | Boddey [number of proteins (%)] | Sargeant [number of proteins (%)] | van Ooij [number of proteins (%)] | Confirmed export | |||
|---|---|---|---|---|---|---|---|---|
| Common, confirmed | A | 83 | 22.3 | 82 | 20.7 | 70 | 25.3 | FIKK kinase 10.1, GBP130, EMP3, STEVOR, KAHRP |
| C | 92 | 24.7 | 93 | 23.5 | 87 | 31.4 | Rifin (PFA0745w/PF3D7_0115300) | |
| S | 105 | 28.2 | 114 | 28.9 | 71 | 25.6 | FIKKs, MESA, REX3, REX4, RIFIN | |
| T | 24 | 6.4 | 26 | 6.6 | 18 | 6.5 | FIKK4.1, Hyp1 (PF3D7_0113300) | |
| Y | 21 | 5.7 | 26 | 6.6 | 9 | 3.3 | FIKK11, RESA | |
| Total | 325 | 87.4 | 341 | 86.1 | 255 | 92.1 | ||
| Uncommon, confirmed | G | 7 | 1.9 | 5 | 1.3 | 5 | 1.8 | Rifin, PTP2, Pf3D7_0801000 (PfPHIST_0801), PVX_093680 (PHIST CVC8195) |
| H | 3 | 0.8 | 2 | 0.5 | 2 | 0.7 | HRPII, HRPIII | |
| L | 11 | 3.0 | 10 | 2.5 | 1 | 0.4 | FIKK7.1 | |
| N | 5 | 1.3 | 9 | 2.3 | 0 | 0 | GARP, FIKK | |
| V | 7 | 1.9 | 8 | 2.0 | 4 | 1.44 | GEXP18 | |
| Total | 33 | 8.9 | 34 | 8.6 | 12 | 4.3 | ||
| None confirmed, unlikely | E | 1 | 0.3 | 3 | 0.8 | 0 | 0 | |
| F | 4 | 1.1 | 4 | 1.0 | 3 | 1.1 | ||
| K | 5 | 1.4 | 5 | 1.3 | 4 | 1.4 | ||
| R | 0 | 0 | 1 | 0.4 | ||||
| Total | 10 | 2.7 | 12 | 3.0 | 8 | 2.9 | ||
| Not confirmed | I | 4 | 1.1 | 9 | 2.3 | 2 | 0.7 | |
| Not observed | D | 0 | 0 | 0 | 0 | 0 | 0 | |
| M | 0 | 0 | 0 | 0 | 0 | 0 | ||
| P | 0 | 0 | 0 | 0 | 0 | 0 | ||
| Q | 0 | 0 | 0 | 0 | 0 | 0 | ||
| W | 0 | 0 | 0 | 0 | 0 | 0 | ||
| Total | 372 | 100 | 396 | 100 | 277 | 100 | ||
a
For references for confirmation of protein export, please see text. For further information, please see Fig. S5.