Table 1.

In vitro growth inhibitory activity (IC₅₀ ± SD, µM) of 27a, 36a, and 36b^a.

Compound	A549	HCT-116	MCF-7	U-2 OS	U-87 MG	HEK293
27a	0.26 ± 0.12	0.22 ± 0.04	0.79 ± 0.21	0.37 ± 0.05	0.45 ± 0.15	0.19 ± 0.07
36a	0.93 ± 0.15	0.48 ± 0.06	1.39 ± 0.29	0.99 ± 0.18	2.19 ± 0.30	1.65 ± 0.13
36b	0.60 ± 0.10	0.27 ± 0.11	0.83 ± 0.21	0.71 ± 0.06	1.40 ± 0.24	0.32 ± 0.11
Etoposide	0.54 ± 0.21	0.39 ± 0.01	0.83 ± 0.15	0.61 ± 0.04	11.86 ± 1.31	1.91 ± 0.97

^a Values represent a concentration that inhibits 50% of cell growth and are means of three independent experiments. Etoposide was used as a reference.