Table 4.
Univariate and Multivariate Logistic Regression Analysis of Risk Factors for Late Postoperative Complications in Ulcerative Colitis Patients with IPAA
| Variable | Non-late postoperative complications group (n=137) | Late postoperative complications group (n=71) | Univariate analysis p-value |
Multivariate logistic regression | ||
|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | |||||
| Age at diagnosis | ||||||
| <40 yr | 69 (50.4) | 31 (43.7) | 0.359* | |||
| ≥40 yr | 68 (49.6) | 40 (56.3) | ||||
| Body mass index | 0.567* | |||||
| ≥18.5 kg/m2 | 96 (70.1) | 47 (66.2) | ||||
| <18.5 kg/m2 | 41 (29.9) | 24 (33.8) | ||||
| Disease duration | 0.653* | |||||
| <5 yr | 93 (67.9) | 46 (64.8) | ||||
| ≥5 yr | 44 (32.1) | 25 (35.2) | ||||
| First occurrence | 0.002† | 8.102 (2.259–29.602) | 0.001 | |||
| Yes | 28 (20.4) | 3 (4.2) | ||||
| No | 109 (79.6) | 68 (95.8) | ||||
| Extent of ulcerative colitis | 0.214† | |||||
| E1 (proctitis) | 27 (19.7) | 10 (14.1) | ||||
| E2 (left-sided colitis) | 13 (9.5) | 5 (7.0) | ||||
| E3 (pancolitis) | 97 (70.8) | 56 (78.9) | ||||
| Extraintestinal manifestation | 0.712* | |||||
| No | 122 (89.1) | 62 (87.3) | ||||
| Yes | 15 (10.9) | 9 (12.7) | ||||
| Mesalamine | 0.183* | |||||
| No | 45 (32.8) | 17 (23.9) | ||||
| Yes | 92 (67.2) | 54 (76.1) | ||||
| Immunomodulators | 0.220* | |||||
| No | 93 (67.9) | 54 (76.1) | ||||
| Yes | 44 (32.1) | 17 (23.9) | ||||
| Steroids | 0.554* | |||||
| No | 54 (39.4) | 25 (35.2) | ||||
| Yes | 83 (60.6) | 46 (64.8) | ||||
| Biologics | 0.606* | |||||
| No | 116 (84.7) | 62 (87.3) | ||||
| Yes | 21 (15.3) | 9 (12.7) | ||||
| Stage of surgery | 0.373† | |||||
| II-stage IPAA | 84 (61.3) | 48 (67.6) | ||||
| III-stage IPAA | 53 (38.7) | 23 (32.3) | ||||
| Surgical urgency | 0.682† | |||||
| Urgent surgery | 14 (10.2) | 6 (8.5) | ||||
| Elective surgery | 123 (89.8) | 65 (91.5) | ||||
| Surgical approach | 0.705* | |||||
| Open surgery | 39 (28.5) | 22 (31.0) | ||||
| Laparoscopic surgery | 98 (71.5) | 49 (69.0) | ||||
| Pouch length | 0.042* | 3.100 (1.519–6.329) | 0.002 | |||
| Short J pouch | 55 (40.1) | 39 (54.9) | ||||
| Long J pouch | 82 (59.9) | 32 (45.1) | ||||
| Hemoglobin | 0.532* | |||||
| ≥110 g/L | 48 (35.0) | 28 (39.4) | ||||
| <110 g/L | 89 (65.0) | 43 (60.6) | ||||
| Albumin | 0.104* | |||||
| ≥35 g/L | 59 (43.1) | 39 (54.9) | ||||
| <35 g/L | 78 (56.9) | 32 (45.1) | ||||
| White blood cell | 0.031* | 2.641 (1.243–5.609) | 0.012 | |||
| <10×109/L | 111 (81.1) | 48 (67.6) | ||||
| ≥10×109/L | 26 (19.0) | 23 (32.4) | ||||
| Hospitalization time | 0.003* | 1.626 (0.820–3.226) | 0.164 | |||
| <15 day | 78 (56.9) | 25 (35.2) | ||||
| ≥15 day | 59 (43.1) | 46 (64,8) | ||||
| Intraoperative blood loss | 0.009* | 3.484 (1.574–7.712) | 0.002 | |||
| <200 mL | 100 (73.0) | 39 (54.9) | ||||
| ≥200 mL | 37 (27.0) | 32 (45.1) | ||||
Data are presented as number (%).
IPAA, ileal pouch-anal anastomosis; OR, odds ratio; CI, confidence interval.
*Chi-square test; †Wilcoxon rank-sum test.