Fig. 1. Clinical and biological parameters’ importance.
We performed random forest, gradient boosting machine, extreme gradient boosting tree, linear discriminant analysis, model averaged neural network, and multinomial logistic regression to measure the parameter importance for predicting the day-zero biopsy histological lesion scores during the derivation process. The importance was then averaged for the ensemble model. a Donor parameter importance for arteriosclerosis (cv Banff score). b Donor parameter importance for arteriolar hyalinosis (ah Banff score). c Donor parameter importance for interstitial fibrosis and tubular atrophy (IFTA Banff score). d Donor parameter importance for the percentage of sclerotic glomeruli (glomerulosclerosis score). Banff scores: cv arteriosclerosis, ah arteriolar hyalinosis, IFTA interstitial fibrosis and tubular atrophy. BMI body mass index, DCD donation after circulatory death, HCV hepatitis C virus. Source data are provided as a Source Data file.