Figure 1.

Training with zymosan and β-glucans induce different cytokine responses to LPS. (A) Experimental scheme. (B) TNF ELISA from supernatants of macrophages stimulated with LPS for 8 h, after training with the indicated ligands; p-values derived from two-tailed t-test; β-glu_ETSU = β-glucan from East Tennessee State University, β-glu_DZ = depleted zymosan. (C) Heat map of multiplexed cytokine bead array from supernatant of macrophages stimulated with LPS for 8 h, after training with the indicated ligands; replicate columns within a condition are from a different donors.