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. 2024 Jan 3;14:1230608. doi: 10.3389/fphar.2023.1230608

TABLE 6.

Classification statistics for antioxidant effects of active substances extracted from the coral.

Active ingredient Source Mechanism Concentration Reference
Sesquiterpenoids Sinularia sp. Oxidative free radical absorption 5.36 units (1 mM of Trolox equivalent) per 0.31 mg/mL (IC50) Zhang et al. (2006a)
Steroids Lipid peroxidation (Vit C/Fe2+ excited) 7.6, 30.6, and 122.2 µmol/L (IC50) Xu et al. (1997)
pseudopterosin I Sinularia suberosa Free radical scavenging:·OH, O2-, DPPH 0.1006, 0.1001, and 0.021 mg/mL (IC50) Xiang (2016)
pseudopterosin II Sinularia suberosa Free radical scavenging:·OH, O2-, DPPH 0.2509, 0.2519, and 0.053 mg/mL (IC50) Xiang (2016)
Cladiellin A Cladiella sp. Oxidative free radical absorption 3.151, 4.781, and 5.171 µM (IC50) Zhang et al. (2005b)
Sinularin Free radical scavenging: DPPH, ABTS+, and OH 250–400 µM (Y) Wang et al. (2021)
Dihydrosinularin Free radical scavenging: DPPH, ABTS+, and OH 200–400 µM (Y) Wang et al. (2021)
Lobocompactols A Lobophytum compactum Oxidative free radical absorption 1.4 and 1.3 µM Trolox equivalents, respectively, at a concentration of 5 µM (IC50) Chau et al. (2011)
Lobocompactols B Lobophytum compactum Oxidative free radical absorption 1.4 and 1.3 µM Trolox equivalents, respectively, at a concentration of 5 µM (IC50) Chau et al. (2011)
BCE Free radical scavenging: DPPH, OH, and Lipid peroxidation Bai (2011)