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. 2024 Jan 3;15:1292524. doi: 10.3389/fnagi.2023.1292524

Table 3.

SHR for PDD in the patients without diabetes according to glucose variability (CV).

Model 1* Model 2**
SHR (95% CI) p value SHR (95% CI) p value
quartile 1 1 (ref) 1 (ref)
quartile 2 1.18 (0.96–1.45) 0.120 1.18 (0.96–1.45) 0.120
quartile 3 1.21 (0.98–1.49) 0.084 1.20 (0.97–1.49) 0.088
quartile 4 1.47 (1.19–1.82) <0.001 1.46 (1.17–1.83) 0.001

*Model 1 was adjusted for age, sex, presence of hypertension and hyperlipidemia, heavy alcohol consumption, smoking, and regular exercise in the Fine and Gray competing regression model, including glucose variability as a separate predictor and death as a competing risk.

**Model 2 was adjusted for all covariates in model 1 plus systolic BP, diastolic BP, fasting glucose, total cholesterol, and BMI at index health examination in the Fine and Gray competing regression model.

SHR, subdistributional hazard ratio; PDD, Parkinson’s disease dementia; CV, coefficient of variation; BP, blood pressure; BMI, body mass index.