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. 2024 Jan 3;10:1305873. doi: 10.3389/fvets.2023.1305873

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Copyright © 2024 Eichler, Ehrle, Machnik, Jensen, Wagner, Baudisch, Bolk, Pötzsch, Thevis, Bäumer, Lischer and Wiegard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cortisol levels in serum (A) and saliva (B) before the novel object test (NOT) and trailer test, and immediately after both tests. Tests were performed twice: prior to start of paste administrations (baseline) and following 13 days of paste administrations to a treatment and control group (n = 6 + 6 horses). Pool rafts were used as novel objects [pineapple for the baseline test (NOT 1), turtle for the second test (NOT 2)]. The treatment group received a cannabidiol (CBD) containing paste twice daily from days 1 to 15 (3 mg CBD/kg).