Table 2.
Group differences in neuropsychological tests
| df | F | ηp2 | p† | Tukey HSD | ||
|---|---|---|---|---|---|---|
| Episodic memory | RAVLT (Total recall 1–5) | |||||
| group | 1 | 1.988 | 0.020 | 0.162 | ||
| MCI status | 1 | 6.426 | 0.063 | 0.013 | ||
| RAVLT (Trial 6) | ||||||
| group | 1 | 0.969 | 0.010 | 0.327 | ||
| MCI status | 1 | 0.633 | 0.007 | 0.428 | ||
| RAVLT (delayed recall) | ||||||
| group | 1 | 2.650 | 0.027 | 0.107 | ||
| MCI status | 1 | 6.806 | 0.066 | 0.011 | ||
| RAVLT (recognition) | ||||||
| group | 1 | 3.338 | 0.034 | 0.071 | ||
| MCI status | 1 | 5.778 | 0.057 | 0.018 | ||
| MIST (event-based) | ||||||
| group | 1 | 2.543 | 0.026 | 0.114 | ||
| MCI status | 1 | 0.079 | 0.001 | 0.779 | ||
| MIST (time-based) | ||||||
| group | 1 | 0.014 | < 0.001 | 0.907 | ||
| MCI status | 1 | 8.123 | 0.078 | 0.005 | ns | |
| MBT (Total Cued Recall) | ||||||
| group | 1 | 0.093 | 0.001 | 0.761 | ||
| MCI status | 1 | 1.378 | 0.014 | 0.243 | ||
| MBT (Paired Recall Pairs) | ||||||
| group | 1 | 0.104 | 0.001 | 0.747 | ||
| MCI status | 1 | 1.302 | 0.013 | 0.257 | ||
| MBT (Total Delayed Paired Recall) | ||||||
| group | 1 | 0.021 | < 0.001 | 0.885 | ||
| MCI status | 1 | 2.449 | 0.025 | 0.121 | ||
| MBT (Delayed Paired Recall Pairs) | ||||||
| group | 1 | 0.003 | < 0.001 | 0.956 | ||
| MCI status | 1 | 0.926 | 0.010 | 0.338 | ||
| MBT (Total Free Recall) | ||||||
| group | 1 | 0.246 | 0.003 | 0.621 | ||
| MCI status | 1 | 2.097 | 0.021 | 0.151 | ||
| MBT (Total Delayed Free Recall) | ||||||
| group | 1 | 0.129 | 0.001 | 0.720 | ||
| MCI status | 1 | 7.743 | 0.075 | 0.006 | ns | |
| Attention / working memory | LNS | |||||
| group | 1 | 0.050 | 0.001 | 0.824 | ||
| MCI status | 1 | 3.426 | 0.034 | 0.067 | ||
| TMT-A | ||||||
| group | 1 | 0.562 | 0.006 | 0.455 | ||
| MCI status | 1 | 25.699 | 0.211 | < 0.001 |
HC > iRBD-MCI; iRBD-MCI < iRBD-NC |
|
| Executive functions | PST (colors) | |||||
| group | 1 | 0.020 | < 0.001 | 0.888 | ||
| MCI status | 1 | 4.213 | 0.042 | 0.043 | ||
| PST (interference) | ||||||
| group | 1 | 0.139 | 0.001 | 0.710 | ||
| MCI status | 1 | 7.553 | 0.073 | 0.007 | ns | |
| TMT-B | ||||||
| group | 1 | 1.189 | 0.012 | 0.278 | ||
| MCI status | 1 | 21.29 | 0.182 | < 0.001 |
HC > iRBD-MCI; iRBD-MCI < iRBD-NC |
|
| VF (animals/clothes) | ||||||
| group | 1 | 0.524 | 0.005 | 0.471 | ||
| MCI status | 1 | 2.872 | 0.029 | 0.093 | ||
| Visuospatial functions | CDT | |||||
| group | 1 | 0.022 | < 0.001 | 0.881 | ||
| MCI status | 1 | 6.237 | 0.061 | 0.014 | ||
| MoCA (cube) | ||||||
| group | 1 | 2.923 | 0.030 | 0.091 | ||
| MCI status | 1 | 2.450 | 0.025 | 0.121 | ||
| Processing speed / psychomotor speed | GPT (left hand) | |||||
| group | 1 | 1.146 | 0.012 | 0.287 | ||
| MCI status | 1 | 4.830 | 0.048 | 0.030 | ||
| GPT (right hand) | ||||||
| group | 1 | 0.797 | 0.008 | 0.374 | ||
| MCI status | 1 | 3.997 | 0.040 | 0.048 | ||
| SDMT | ||||||
| group | 1 | 3.469 | 0.035 | 0.066 | ||
| MCI status | 1 | 10.088 | 0.095 | 0.002 |
HC > iRBD-MCI; iRBD-MCI < iRBD-NC |
|
| PST (Dots) | ||||||
| group | 1 | 1.460 | 0.015 | 0.230 | ||
| MCI status | 1 | 8.625 | 0.082 | 0.004 | iRBD-MCI < iRBD-NC | |
| PST (words) | ||||||
| group | 1 | 0.984 | 0.010 | 0.324 | ||
| MCI status | 1 | 4.236 | 0.042 | 0.042 | ||
| Language | VF (K) | |||||
| group | 1 | 1.963 | 0.020 | 0.164 | ||
| MCI status | 1 | 10.767 | 0.101 | 0.001 | iRBD-MCI < iRBD-NC | |
| VF (action verb) | ||||||
| group | 1 | 0.009 | < 0.001 | 0.926 | ||
| MCI status | 1 | 0.527 | 0.005 | 0.470 | ||
| VF (vegetables) | ||||||
| group | 1 | 0.736 | 0.008 | 0.393 | ||
| MCI status | 1 | 4.269 | 0.043 | 0.042 | ||
Summary of the nested ANOVAs with fixed factors group (iRBD, HC) and MCI status (NC, MCI) on demographically adjusted z-scores. df degrees of freedom, F F statistic, ηp2 partial eta squared. HC healthy controls, iRBD isolated rapid eye movement sleep behavior disorder, MCI mild cognitive impairment, NC normal cognition, ns not significant post hoc test, RAVLT Rey Auditory Verbal Learning Test, MBT Memory Binding Test, MIST Memory for Intentions Screening Test, TMT Trial Making Test, LNS Letter-Number Sequencing from Wechsler Adult Intelligence Scale, Third Revision, PST Prague Stroop Test, VF Verbal fluency, CDT Clock Drawing Test, GPT Grooved Pegboard Test, MoCA Montreal Cognitive Assessment, SDMT Symbol Digit Modalities Test
†p values < 0.05 after Benjamini–Hochberg correction are in bold