Table 2.
Diagnostic procedures provided by Italian CCDDs directly or by agreement at the national level and by geographical macro-area, data are expressed as N (%) or median (interquartile range—IQR) and mean (min–max)
| Diagnostic assessment | Italy (n = 450) | North (n = 202) | Center (n = 82) | South/Islands (n = 166) | p |
|---|---|---|---|---|---|
| Services provided directly or by agreement, N (%) | |||||
| Clinic assessment | 450(100.0%) | 202 (100.0%) | 82 (100.0%) | 166 (100.0%) | 1.000 |
| Neuropsychological assessment | 423 (94.0%) | 197 (97.5%) | 75 (91.5%) | 151 (91.0%) | 0.012 |
| ECG and cardiological examination | 382 (84.9%) | 176 (87.1%) | 65 (79.3%) | 141 (84.9%) | 0.245 |
| Blood tests | 371 (82.4%) | 175 (86.6%) | 62 (75.6%) | 134 (80.7%) | 0.066 |
| Brain MRI | 366 (81.3%) | 171 (84.7%) | 65 (79.3%) | 130 (78.3%) | 0.260 |
| CT Brain scan | 366 (81.3%) | 169 (83.7%) | 63 (76.8%) | 134 (80.2%) | 0.395 |
| EEG | 351 (78.0%) | 168 (83.2%) | 60 (73.2%) | 123 (74.1%) | 0.057 |
| PET FDG | 335 (74.4%) | 165 (81.7%) | 57 (69.5%) | 113 (68.1%) | 0.006 |
| SPECT | 314 (69.8%) | 148 (73.3%) | 51 (62.2%) | 115 (69.3%) | 0.181 |
| PET amyloid | 300 (66.7%) | 142 (70.3%) | 53 (64.6%) | 105 (63.3%) | 0.329 |
| Ordinary hospitalization | 297 (66.0%) | 142 (70.3%) | 61 (74.4%) | 94 (56.6%) | 0.005 |
| CSF markers | 281 (62.4%) | 153 (75.7%) | 47 (57.3%) | 81 (48.8%) | < 0.001 |
| Genetic testing | 254 (56.4%) | 126 (62.4%) | 44 (53.7%) | 84 (50.6%) | 0.065 |
| Day hospital | 242 (53.8%) | 115 (56.9%) | 45 (54.9%) | 82 (49.4%) | 0.345 |
| Plasma markers | 222 (49.3%) | 120 (59.4%) | 31 (37.8%) | 71 (42.8%) | < 0.001 |
| Genetic counseling | 218 (48.4%) | 106 (52.5%) | 34 (41.5%) | 78 (47.0%) | 0.217 |
| Functional neuroimaging | 193 (42.9%) | 79 (39.1%) | 32 (39.0%) | 82 (49.4%) | 0.103 |
| Volumetric resonance | 182 (40.4%) | 74 (36.6%) | 32 (39.0%) | 76 (45.8%) | 0.197 |
| EEG with brain connectivity assessment | 150 (33.3%) | 61 (30.2%) | 23 (28.0%) | 66 (39.8%) | 0.082 |
| Total number of neuropsychological tests used | |||||
| Median (IQR) | 23 (12–31) | 28 (21–34) | 22 (9–31) | 14 (8–24) | < 0.001 |
| Mean (min–max) | 22 (0–50) | 27 (3–50) | 21 (0–50) | 17 (1–49) | |
ECG echocardiogram, MRI magnetic resonance imaging, CT computer tomography, EEG electroencephalogram, PET FDG positron emission tomography fluor deoxy glucose, SPECT single photon emission computed tomography, CSF cerebrospinal fluid