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. 2024 Jan 3;14:1230861. doi: 10.3389/fphar.2023.1230861

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Copyright © 2024 Shen, Wu, Chen, Bai, Liu, Jiang, Zhang and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PCA score plot, OPLSDA score plot, and ermutation test plot of the OPLS-DA models. ((A) PCA score plot of the control group, model group, positive group, and the third-grade group of RAS in plasma via positive and negative model; (B) PCA score plot of the control group, model group, positive group, and the third-grade group of RAS in urine via positive and negative model; (C) OPLS-DA score plot of the control group and model group in plasma via positive and negative model; (D) OPLS-DA score plot of the control group and model group in urine via positive and negative model; (E) The control group and model group samples of 200 permutation times in plasma via positive and negative model; (F) The control group and model group samples of 200 permutation times in urine via positive and negative model).