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. 2024 Jan 3;14:1332777. doi: 10.3389/fimmu.2023.1332777

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Copyright © 2024 Verma, Croft, Greenwood, Stephens, Malladi, Nunnick, Zuo, Kinsella and Moss

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed serum protein markers at Day-14 post SCT by clinical outcome. Results of Univariate testing of Day 14 serum protein levels stratified by clinical outcomes Acute GvHD: Yes (44) vs No (105) (A); Chronic GvHD: Yes (22) vs No (122) (B); Relapse: Yes (44) vs No (105) (C); Survival: Deceased (D) (52) vs Alive (A) (100) (D). Proteins labelled in red showed a significant difference (p<0.05) by Man Whitney after Benjamini-Hochberg (BH) multiple testing correction. FC estimate is calculated as -1*(median difference between samples from eac distribution). Violin plots of Normalised Protein eXpression (NPX) are shown for the proteins found to be differentially expressed for each clinical outcome. (BH corrected p≤0.01**; p≤0.05*).