TABLE 4.

Analysis of the main function of the deregulated miRNAs on our model of chronic daunorubicin-induced cardiomyopathy in rabbit.

Function	miRNA
DNA damage response	let-7f-2-3p, miR-20b-5p, miR-21-3p, miR-21-5p, miR-34a
Oxidative stress	miR-34a
Apoptosis	miR-21-3p, miR-21-5p, miR-34a
Autophagy	miR-21-3p, miR-21-5p, miR-34a
Calcium homeostasis	miR-20b-5p, miR-223
Abnormal vascular homeostasis	miR-21, miR-34, miR-155, miR-433, miR-1298
Inflammatory response	miR-21, miR-34
Fibrosis	miR-21, miR-34, miR-155, miR-433