Table 2.

Evaluation of instrumental variables.

SNPs for IV		Follistatin level (exposure)
Chr	Position	SNP ID	MAF	beta	SE
9	92228559	rs10908903	0.4587	0.0603	0.0109
2	27730940	rs1260326	0.6024	−0.1323	0.0106
15	43726625	rs150844304	0.0294	0.2466	0.0321
5	53327571	rs31226	0.5979	−0.1289	0.0107
12	57791833	rs7974833	0.235	0.0849	0.0123

IV, instrumental variable; Chr, chromosome; SNP, single nucleotide polymorphism; MAF, minor allele frequency; Beta, the effect size; R², IV explains the extent of exposure.