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. 2024 Jan 16;14:1441. doi: 10.1038/s41598-024-51315-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Presence of subretinal fluid and intraretinal fluid in switched patients (a) and naïve patients (b) at different time points. 70 patients were analyzed, 54 in the switched group, 16 in the naïve group. Number of patients affected by any kind of fluid is shown in the y-axis, timepoints in the x-axis (T0 = baseline; T1 = after the loading phase; T2 = at week 24; T3 = at last follow-up). Dark grey columns represent subretinal fluid; light grey columns represent intraretinal fluid; white columns represent dry macula. In both study groups, the number of patients presenting any kind of fluid was statistically reduced at every timepoint compared to T0 (p < 0.05), with consequent increase in the number of patients with dry macula.