Table 1.
Clinical characteristics of patients in the study cohort
| Cases with Primary Hyperparathyroidism n=108,869 | Matched Controls n=1,088,690 | |
|---|---|---|
|
| ||
| Sex | ||
| Male | 23283 (21.4%) | 232830 (21.4%) |
| Female | 85586 (78.6%) | 855860 (78.6%) |
|
| ||
| Race | ||
| White | 87948 (80.8%) | 832279 (76.5%) |
| Black | 12286 (11.3%) | 122325 (11.2%) |
| Hispanic | 5167 (4.8%) | 80145 (7.4%) |
| Other/Unknown | 3468 (3.2%) | 53941 (5.0%) |
|
| ||
|
| ||
| Hypertension | 98994 (90.9%) | 989940 (90.9%) |
|
| ||
| Diabetes | 50426 (46.3%) | 504260 (46.3%) |
|
| ||
| Hyperlipidemia | 99227 (91.1%) | 992270 (91.1%) |
|
| ||
| Tobacco Use | 22972 (21.1%) | 229720 (21.1%) |
|
| ||
| Alcohol Use Disorder* | 1460 (1.3%) | 16663 (1.5%) |
|
| ||
| Family History of Stroke* | 1071 (1.0%) | 8312 (0.8%) |
|
| ||
| Family History of Heart Disease * | 5629 (5.2%) | 48131 (4.4%) |
|
| ||
| Hormone Replacement Therapy * | 2141 (2.0%) | 19290 (1.8%) |
|
| ||
| Kidney Disease * | 29842 (27.4%) | 169736 (15.6%) |
|
| ||
| Parathyroidectomy ** | 40481 (37.2%) | NA |
|
| ||
| Cinacalcet Use ** | 9362 (8.6%) | NA |
*
Controls were not matched on these variables
**
Patients with claims codes for these treatments were excluded from the control group
NA: not applicable