SARS-CoV-2-specific antibody responses in children
(A) The demographic characteristics of 71 unvaccinated children included in this study. Age, gender, SARS-CoV-2 vaccination status, SARS-CoV-2 serology and collection date are shown.
(B) Proportion of children exhibiting antibody responses to SARS-CoV-2 spike (S) and nucleocapsid (N) proteins.
(C) The magnitude of SARS-CoV-2 S and N IgG antibodies (OD490nm) measured by ELISA in seropositive children (n = 41). The dotted lines indicate the cut-off for positivity which was calculated as the mean optical density of COVID-19 prepandemic control samples. Statistical analysis was performed using the Wilcoxon signed rank test; p values < 0.05 were considered statistically significant and are bolded.
See also Figure S1.