Table 1. Concentration and persistence in the body of spike antigens after mRNA-mediated vaccination.

*: [87], **: [88], ***: [89]

BNT162b: Pfizer/BioNTech vaccine, mRNA-1273: Moderna vaccine

Antigen	Vaccination	Concentration (pg/mL)	Time in the body (days)
S*	BNT162b mRNA-1273	Days 1-2 after the first dose - median S levels: 47 pg/mL (plasma)	Present at least 1-2 days (plasma) and 60 days (germinal centers and lymph nodes) post-second dose
		Day 7 after the first dose - median S levels: 1.7 pg/mL (plasma)
		Days 1-2 after the second dose - median S levels: 1.2 pg/mL (plasma)
S, S1**	mRNA-1273	Mean S peak levels: 62±13 pg/mL (plasma)	S present up to 15 days post-first dose, undetectable after the second dose (plasma)
		Mean S1 peak levels: 68±21 pg/mL (plasma)	S1 present up to 14 days post-first dose, undetectable after the second dose, peak levels at 5 days (plasma)
Sfragments***	BNT162b mRNA-1273	-	69-187 days post-vaccination (plasma)