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. 2024 Jan 15;11:22–30. doi: 10.33393/grhta.2024.2696

TABLE I -.

Baseline characteristics of patients on hemodialysis with/without CKD-aP

  CKD-aP patients (n = 218) Non-CKD-aP patients (n = 1,021) p-Value
CKD-aP = chronic kidney disease-associated pruritus.
*Differences statistically significant (p-value <0.05) through a chi-square test between distributions for distributions by age, and through a chi-square test between frequencies for demographics and comorbidities.
Males (n; %) 121; 55.5 583; 57.1 0.72
Median age (Q1; Q3) 71 (61; 80) 68 (53; 79) 0.07
Mean age (±standard deviation) 69 (±13) 66 (±15)  
Distribution by age group (n; %) 0.03*
 <18 0; 0.0 2; 0.2  
 18-29 2; 0.9 8; 0.8  
 30-39 3; 1.4 39; 3.8  
 40-49 10; 4.6 118; 11.6  
 50-59 30; 13.8 156; 15.3  
 60-69 59; 27.1 235; 23.0  
 70-79 61; 28.0 263; 25.8  
 ≥80 53; 24.3 200; 19.6  
Total 218; 100.0 1,021; 100.0  
Potential CKD-aP-related comorbidities (n; %)  
 Hyperphosphatemia 150; 68.8 623; 61.0 0.03*
 Hyperparathyroidism 102; 46.8 437; 42.8 0.3
 Anemia 81; 37.2 364; 35.7 0.7
 Hyperuricemia 36; 16.5 178; 17.4 0.7
Other comorbidities of interest (n; %)  
 Arterial hypertension 162; 74.3 732; 71.7 0.4
 Diabetes mellitus 57; 26.1 195; 19.1 0.01*
 Hypothyroidism 41; 18.8 138; 13.5 0.04*
 Depression 31; 14.2 85; 8.3 0.007*
 Coronary artery disease 21; 9.6 86; 8.4 0.6
 Viral hepatopathies 2; 0.9 5; 0.5 0.4