TABLE I -.
Baseline characteristics of patients on hemodialysis with/without CKD-aP
CKD-aP patients (n = 218) | Non-CKD-aP patients (n = 1,021) | p-Value | |
---|---|---|---|
CKD-aP = chronic kidney disease-associated pruritus. | |||
*Differences statistically significant (p-value <0.05) through a chi-square test between distributions for distributions by age, and through a chi-square test between frequencies for demographics and comorbidities. | |||
Males (n; %) | 121; 55.5 | 583; 57.1 | 0.72 |
Median age (Q1; Q3) | 71 (61; 80) | 68 (53; 79) | 0.07 |
Mean age (±standard deviation) | 69 (±13) | 66 (±15) | |
Distribution by age group (n; %) | 0.03* | ||
<18 | 0; 0.0 | 2; 0.2 | |
18-29 | 2; 0.9 | 8; 0.8 | |
30-39 | 3; 1.4 | 39; 3.8 | |
40-49 | 10; 4.6 | 118; 11.6 | |
50-59 | 30; 13.8 | 156; 15.3 | |
60-69 | 59; 27.1 | 235; 23.0 | |
70-79 | 61; 28.0 | 263; 25.8 | |
≥80 | 53; 24.3 | 200; 19.6 | |
Total | 218; 100.0 | 1,021; 100.0 | |
Potential CKD-aP-related comorbidities (n; %) | |||
Hyperphosphatemia | 150; 68.8 | 623; 61.0 | 0.03* |
Hyperparathyroidism | 102; 46.8 | 437; 42.8 | 0.3 |
Anemia | 81; 37.2 | 364; 35.7 | 0.7 |
Hyperuricemia | 36; 16.5 | 178; 17.4 | 0.7 |
Other comorbidities of interest (n; %) | |||
Arterial hypertension | 162; 74.3 | 732; 71.7 | 0.4 |
Diabetes mellitus | 57; 26.1 | 195; 19.1 | 0.01* |
Hypothyroidism | 41; 18.8 | 138; 13.5 | 0.04* |
Depression | 31; 14.2 | 85; 8.3 | 0.007* |
Coronary artery disease | 21; 9.6 | 86; 8.4 | 0.6 |
Viral hepatopathies | 2; 0.9 | 5; 0.5 | 0.4 |