TABLE 3.
Parameter | Baseline | 2 weeks later | 5 months later | 1 year after diagnosis |
NYHA FC | IV | III | II | IV |
6MWD, m | NA | 351 | 462 | NA |
BNP, ng·L−1 | 1083 | 159 | 63 | 747 |
RAP, mmHg | 12 | NA | 3 | 16 |
mPAP, mmHg | 37 | NA | 26 | 52 |
CO, L·min−1 | 2.7 | NA | 5.8 | 2.5 |
CI, L·min−1·m−2 | 1.9 | NA | 4.1 | 1.3 |
PVR, WU | 11.3 | NA | 3.5 | 23 |
PaO2, mmHg | 69 | 70 | 50 | |
DLCO, % | NA | 41 | 41 | 25 |
6MWD: 6-min walk distance; BNP: brain natriuretic peptide; CI: cardiac index; CO: cardiac output; DLCO: diffusing capacity of the lung for carbon monoxide; FC: functional class; mPAP: mean pulmonary artery pressure; NA: not available; NYHA: New York Heart Association; PaO2: arterial oxygen tension; PVR: pulmonary vascular resistance; RAP: right atrial pressure; WU: Wood unit.