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. 2023 Oct 17;6(4):709–728. doi: 10.20517/cdr.2023.62

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© The Author(s) 2023.

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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CB17 Scid mice are suitable hosts for SC263-R HNSCC cells when co-injected with 25% Matrigel. (A and B) Tumor kinetics over time after s.c. injection with 1 × 10⁶ SC263-R cells in CB17 Scid: (A) and BALB/c nude; (B) mice (n = 3); (C and D) Tumor kinetics over time after s.c. injection with 1 × 10⁶ SC263-R cells mixed with 25% Matrigel in CB17 Scid: (C) and BALB/c nude; (D) mice (n = 3). Each line represents the data of one individual mouse. HNSCC: Head and neck squamous cell carcinoma; -R: cetuximab-resistant HNSCC cell line; -S: cetuximab-sensitive HNSCC cell line; s.c.: subcutaneous.