TABLE 1:
Characteristics of first-degree relatives of probands with hepatocellular carcinoma
| Characteristic | All relatives (n = 112) | Relatives ≥ 40 years old (n = 65) |
|---|---|---|
| Age (years)a | 42.8 (14.4) | 52.9 (9.1) |
|
| ||
| Female, n (%) | 73 (65.2%) | 43 (66.2%) |
|
| ||
| Controlled attenuation parameter (CAP) | ||
| CAP (dB/m)a | 273.5 (62.0) | 274.6 (60.2) |
| CAP ≥ 250 dB/m, n (%) | 74 (66.1%) | 46 (70.8%) |
| CAP ≥ 288 dB/m, n (%) | 47 (42.0%) | 26 (40.0%) |
|
| ||
| Liver stiffness with VCTE | ||
| VCTE (kPa)a | 5.8 (5.4) | 6.3 (6.9) |
| VCTE (kPa) ≥ 7 kPa | 19 (17.0%) | 13 (20.0%) |
| VCTE (kPa) ≥ 12 kPa | 4 (3.6%) | 3 (4.6%) |
|
| ||
| FIB-4 indexa | 0.7 (0.4) | 0.9 (0.4) |
|
| ||
| FIB-4 index ≥ 2.67, n (%) | 1 (0.9%) | 1 (1.7%) |
|
| ||
| VCTE (kPa) ≥ 12 kPa and/or FIB-4 ≥ 2.67 | 4 (3.6%) | 3 (4.6%) |
Abbreviations: CAP, controlled attenuation parameter; HbA1c, glycated haemoglobin; VCTE, vibration-controlled transient elastography.
a
Mean (SD).