TABLE 3.
Factors associated with liver fibrosis (liver stiffness measurement ≥ 7 kPa) in first-degree relatives of Mexican American probands with hepatocellular carcinoma
| OR (95% CI)a | p-value | |
|---|---|---|
| Age (1-year increase) | 1.02 (0.98–1.05) | 0.41 |
| Male gender | 0.83 (0.29–2.38) | 0.72 |
| Body mass index ≥ 30kg/m2 | 1.90 (0.67–5.44) | 0.23 |
| Type 2 diabetes | 3.21 (1.12–9.19) | 0.03 |
| Hypercholesterolemia | 1.40 (0.50–3.95) | 0.52 |
| Hypertension | 1.40 (0.50–3.95) | 0.52 |
| Tobacco use | 0.66 (0.14–3.16) | 0.60 |
| Any alcohol use | 0.66 (0.14–3.16) | 0.60 |
| AST ≥ 30 IU/L | 4.00 (1.37–11.71) | 0.01 |
| Albumin < 3.5 g/dl | 5.24 (0.67–39.76) | 0.11 |
Note: Bold values represent the significance of p-value (p < 0.05). Abbreviation: AST, aspartate aminotransferase.
Results from univariable analysis are shown.