Table 2.

Factors Associated With the Rate of Hepatocellular Carcinoma Development in Alcohol-Associated Cirrhosis

Risk factor	Articles, n	Coefficient	95% CI	P value
Age	12	0.19	−0.02 to 0.40	.08
Male	12	0.61	−1.90 to 3.13	.62
BMI	5	−0.14	−0.54 to 0.26	.48
Smoking	4	8.92	5.78–12.06	<.001
Diabetes	9	9.09	0.53–17.65	.04
Decompensation	8	2.45	0.14–4.77	.04
Ascites	5	0.50	−2.20 to 3.20	.72
Mean bilirubin	7	0.001	−0.02 to 0.02	.93
Mean albumin	7	0.01	−0.01 to 0.04	.31
Mean platelet count	6	−0.009	−0.02 to 0.006	.23
AST	5	−0.009	−0.02 to 0.0004	.06
ALT	5	−0.02	−0.04 to 0.005	.11

ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CI, confidence interval.