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. Author manuscript; available in PMC: 2024 Jan 17.
Published in final edited form as: Neuroimage. 2020 May 23;218:116980. doi: 10.1016/j.neuroimage.2020.116980

Table 1.

Association of subjective effects measures with amplitude of low frequency fluctuations (ALFF) in blood-oxygenation level-dependent (BOLD) signal in left and right claustrum, insula, and putamen regions of interest. Statistics are limited to equations involving a subjective effect that significantly predicted ALFF in at least one region of interest. ß = standardized regression coefficient of the independent variable. Equations where the independent variable is significant (critical α = 0.05, uncorrected) are presented in bold font. MEQ: mystical experience questionnaire.

Equation (dependent variable ~ independent variable) ß t F p (unc) R2adj
left claustrum ALFF ~ overall strength of drug effect −0.0008 2.069 4.28 0.059 0.189
left claustrum ALFF ~ brief total MEQ −0.008 2.239 5.01 0.043 0.223
left claustrum ALFF ~ ineffability −0.0006 2.519 6.35 0.026 0.276
right claustrum ALFF ~ overall strength of drug effect −0.001 3.269 10.7 0.006 0.409
right claustrum ALFF ~ brief total MEQ −0.0008 1.975 3.9 0.069 0.172
right claustrum ALFF ~ ineffability −0.0008 3.287 10.8 0.006 0.412
left insula ALFF ~ overall strength of drug effect −2.67e-05 0.077 0.006 0.939 −0.076
left insula ALFF ~ brief total MEQ −0.0002 0.660 0.436 0.521 −0.042
left insula ALFF ~ ineffability −3.89e-05 0.172 0.029 0.866 −0.075
right insula ALFF ~ overall strength of drug effect 7.17e-05 0.342 0.117 0.738 −0.067
right insula ALFF ~ brief total MEQ −4.49e-05 0.241 0.058 0.813 −0.072
right insula ALFF ~ ineffability 1.15e-06 0.008 7.03e-05 0.993 −0.077
left putamen ALFF ~ overall strength of drug effect −9.03e-05 0.477 0.227 0.642 −0.058
left putamen ALFF ~ brief total MEQ −1.78e-05 0.105 0.011 0.918 −0.076
left putamen ALFF ~ ineffability 3.38e-05 0.271 0.073 0.791 −0.071
right putamen ALFF ~ overall strength of drug effect −0.0003 1.137 1.29 0.276 0.020
right putamen ALFF ~ brief total MEQ −0.0002 0.829 0.687 0.422 −0.023
right putamen ALFF ~ ineffability −0.0002 1.126 1.27 0.280 0.019