Table 1.
Association of subjective effects measures with amplitude of low frequency fluctuations (ALFF) in blood-oxygenation level-dependent (BOLD) signal in left and right claustrum, insula, and putamen regions of interest. Statistics are limited to equations involving a subjective effect that significantly predicted ALFF in at least one region of interest. ß = standardized regression coefficient of the independent variable. Equations where the independent variable is significant (critical α = 0.05, uncorrected) are presented in bold font. MEQ: mystical experience questionnaire.
Equation (dependent variable ~ independent variable) | ß | t | F | p (unc) | R2adj |
---|---|---|---|---|---|
left claustrum ALFF ~ overall strength of drug effect | −0.0008 | 2.069 | 4.28 | 0.059 | 0.189 |
left claustrum ALFF ~ brief total MEQ | −0.008 | 2.239 | 5.01 | 0.043 | 0.223 |
left claustrum ALFF ~ ineffability | −0.0006 | 2.519 | 6.35 | 0.026 | 0.276 |
right claustrum ALFF ~ overall strength of drug effect | −0.001 | 3.269 | 10.7 | 0.006 | 0.409 |
right claustrum ALFF ~ brief total MEQ | −0.0008 | 1.975 | 3.9 | 0.069 | 0.172 |
right claustrum ALFF ~ ineffability | −0.0008 | 3.287 | 10.8 | 0.006 | 0.412 |
left insula ALFF ~ overall strength of drug effect | −2.67e-05 | 0.077 | 0.006 | 0.939 | −0.076 |
left insula ALFF ~ brief total MEQ | −0.0002 | 0.660 | 0.436 | 0.521 | −0.042 |
left insula ALFF ~ ineffability | −3.89e-05 | 0.172 | 0.029 | 0.866 | −0.075 |
right insula ALFF ~ overall strength of drug effect | 7.17e-05 | 0.342 | 0.117 | 0.738 | −0.067 |
right insula ALFF ~ brief total MEQ | −4.49e-05 | 0.241 | 0.058 | 0.813 | −0.072 |
right insula ALFF ~ ineffability | 1.15e-06 | 0.008 | 7.03e-05 | 0.993 | −0.077 |
left putamen ALFF ~ overall strength of drug effect | −9.03e-05 | 0.477 | 0.227 | 0.642 | −0.058 |
left putamen ALFF ~ brief total MEQ | −1.78e-05 | 0.105 | 0.011 | 0.918 | −0.076 |
left putamen ALFF ~ ineffability | 3.38e-05 | 0.271 | 0.073 | 0.791 | −0.071 |
right putamen ALFF ~ overall strength of drug effect | −0.0003 | 1.137 | 1.29 | 0.276 | 0.020 |
right putamen ALFF ~ brief total MEQ | −0.0002 | 0.829 | 0.687 | 0.422 | −0.023 |
right putamen ALFF ~ ineffability | −0.0002 | 1.126 | 1.27 | 0.280 | 0.019 |