TABLE 1.
Comparison of in vivo parameters of S. sanguis-infecteda and S. epidermidis-infected vegetations
| Treatment | Infection (log CFU/g) | Wt (mg) | TFA (pmol of FXa/g) |
|---|---|---|---|
| Sterile | None | 14.0 ± 1 | 392 ± 101 |
| Sterile + etoposide | None | 13.0 ± 6 | 249 ± 93 |
| S. sanguis | 8.7 ± 0.7 | 41.0 ± 23 | 736 ± 156 |
| S. sanguis + etoposide | 8.7 ± 0.7 | 31.7 ± 7 | 278 ± 65 |
| Sterile | None | 11.0 ± 5 | 116 ± 23 |
| Sterile + etoposide | None | 11.0 ± 5 | 99 ± 21 |
| S. epidermidis | 7.0 ± 1.2 | 16.0 ± 9 | 162 ± 8 |
| S. epidermidis + etoposide | 7.5 ± 0.9 | 18.0 ± 12 | 158 ± 32 |
| S. sanguis | 8.7 ± 0.7 | 22.4 ± 4.2 | 602 ± 56 |
| S. sanguis + penicillin G | 7.1 ± 0.1 | 21.0 ± 5.8 | 250 ± 50 |
| S. epidermidis | 7.2 ± 1.8 | 18.5 ± 8.7 | 100 ± 19 |
| S. epidermidis + teicoplanin | <3.8 | 18.2 ± 11.9 | 80 ± 9 |
a
Data obtained from reference 4.