Table 2. Exosome-Associated Molecular Significance as an EMT Biomarker.
exosome-related EMT biomarker | exosome source | molecules | function | references |
---|---|---|---|---|
Diagnostic marker | Blood | CD82 | Breast metastasis | (72) |
Serum | miRNA-106b | It associated with lung lymph node metastasis | (74) | |
Serum | circRNA-100 | Liver cancer tumor metastasis | (76) | |
Blood | CD147 | Its high expression in advanced stage colon cancer | (77) | |
Serum | miRNA-182-5p | High expression in brain cancer | (79) | |
Prognostic marker | Plasma | miR-222 | High expression led to NF-κB mediated breast cancer lymphatic metastasis | (73) |
Plasma | miR-21 | Lung cancer | (75) | |
miRNA-4257 | ||||
Serum | miRNA-1262 | Lower expression in liver cancer | (102) | |
Plasma and Serum | miRNA-486-5p | Colon cancer lymph node metastasis | (78) | |
Serum | miRNA-301a | High expression in brain cancer | (80) |