Table 3.

Multivariable competing risks regression model using subdistribution hazard ratios to compare the cumulative incidence of biochemical recurrence across morphology indicators

Variable	SHR (95% CI)	P
Gleason 3	0.48 (0.28, 0.82)	0.006
Gleason 5	1.11 (0.65, 1.89)	0.72
Intraductal carcinoma	1.07 (0.62, 1.87)	0.81
Gleason 4 subpattern
Glomeruloid	0.58 (0.31, 1.08)	0.086
Cribriform	3.50 (1.89, 6.49)	< 0.001
Poorly formed	1.11 (0.54, 2.29)	0.78
Age (years)	0.998 (0.96, 1.03)	0.93
Pre-operative PSA (units)	1.003 (1.000, 1.006)	0.052
Lymph nodes removed	2.14 (1.01, 4.50)	0.046
Lymph nodes positive	1.86 (0.95, 3.64)	0.072
Positive margins	1.17 (0.69, 1.97)	0.56
Stage T2**	Ref.	Ref.
Stage T3a	2.92 (1.49, 5.72)	0.002
Stage T3b	5.99 (2.18, 16.5)	0.001

CI, confidence interval; SHR, subdistribution hazard ratio.

Statistically significant P values are highlighted in bold.

^**Omnibus test of association between stage and cumulative incidence of biochemical recurrence: P < 0.001.