Table 2.
Comparison of Baseline Parameters Among Patients With and Without Muscle Strength Decline.
| MSD + (n = 86) | MSD (n = 14) | P value | |
|---|---|---|---|
| Age (years) | 44.9 (9.9) | 40.8 (6.7) | 0.13 |
| Gender (n) male:female | 74:12 | 12:2 | 0.9 |
| Etiology (n)- alcohol:HCV:HBV:others | 68:8:8:2 | 12:0:0:2 | 0.9 |
| CTP class (n) A:B:C | 0:36:50 | 0:6:8 | 0.9 |
| SARC-F score (n) <4:≥4 | 21:65 | 10:4 | <0.001 |
| Muscle volume loss male:female (n) | 52:8 | 2:0 | <0.001 |
| Body mass index kg/m2 male:female | 21.2 (4.5):19.2 (1.5) | 23.3(4.3):27.8(0.1) | 0.1; <0.001 |
| Total bilirubin, mg/dL | 4.2 (3.8) | 7.6 (4.2) | 0.002 |
| Albumin, g/dL | 2.8 (0.5) | 3.2 (0.4) | 0.005 |
| INR | 1.7 (0.9) | 1.5 (0.5) | 0.4 |
| Creatinine, mg/L | 1.2 (0.6) | 1.1 (0.3) | 0.5 |
| Platelet count, 105/μl | 1.5 (0.8) | 1.4 (0.8) | 0.7 |
| ALT, U/L | 40.5 (24.9) | 76.3 (38.1) | <0.001 |
| AST, U/L | 45.4 (24.2) | 81.8 (33.9) | <0.001 |
Abbreviations: ALT = alanine transaminase; AST = aspartate aminotransferase; CTP = Child–Turcotte–Pugh classification; HBV = hepatitis B virus; HCV = hepatitis C virus; SD = standard deviation; INR = international normalized ratio; MSD = muscle strength decline; SARC-F = (S) strength, (A) assistance while walking, (R) rise from a chair, (C) climb stairs, and (F) falls.
Bold numbers indicates statistically significant values.