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. 2023 Dec 23;79:101860. doi: 10.1016/j.molmet.2023.101860

Figure 9.

Figure 9

Metformin transporters are expressed in the developing hypothalamus. (A) Oct1, (B) Oct3 and (C) Mate1 mRNA expression in the hypothalamus across development in wild-type male mice (n = 5–8/time-point). (D) Oct1, (E) Oct3 and (F) Mate1 mRNA expression in the hypothalamus across development in wild-type female mice (n = 4–10/time-point). Data are expressed as mean ± SEM with single data points in black dots. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 compared to P6, unless indicated. P-values derived from one-way ANOVA followed by Tukey's multiple comparisons. P: postnatal day, W: weeks of age.