Table 8.

Two-way ANOVA results for Figure 6.

Panel	Source of variation	F (DFn, DFd)	P value
A) Total AMPKα levels (males)	Diet	F (2, 29) = 4.82	P = 0.016
	Metformin	F (1, 29) = 2.03	P = 0.165
	Diet x Metformin	F (2, 29) = 0.12	P = 0.890
B) Phosphorylated- AMPKα levels (males)	Diet	F (2, 29) = 4.74	P = 0.017
	Metformin	F (1, 29) = 3.76	P = 0.062
	Diet x Metformin	F (2, 29) = 2.20	P = 0.129
C) pAMPK/AMPK ratio (males)	Diet	F (2, 29) = 0.20	P = 0.816
	Metformin	F (1, 29) = 0.04	P = 0.835
	Diet x Metformin	F (2, 29) = 1.87	P = 0.173
D) Total LKB1 levels (males)	Diet	F (2, 30) = 0.65	P = 0.530
	Metformin	F (1, 30) = 1.21	P = 0.279
	Diet x Metformin	F (2, 30) = 1.89	P = 0.169
E) Phosphorylated-LKB1 levels (males)	Diet	F (2, 30) = 1.07	P = 0.355
	Metformin	F (1, 30) = 0.11	P = 0.740
	Diet x Metformin	F (2, 30) = 0.35	P = 0.710
F) pLKB1/LKB1 ratio (males)	Diet	F (2, 30) = 0.68	P = 0.514
	Metformin	F (1, 30) = 0.34	P = 0.566
	Diet x Metformin	F (2, 30) = 0.17	P = 0.844
G) Total mTOR levels (males)	Diet	F (2, 30) = 0.95	P = 0.396
	Metformin	F (1, 30) = 0.38	P = 0.542
	Diet x Metformin	F (2, 30) = 3.53	P = 0.042
H) Phosphorylated-mTOR levels (males)	Diet	F (2, 29) = 0.84	P = 0.444
	Metformin	F (1, 29) = 1.48	P = 0.233
	Diet x Metformin	F (2, 29) = 0.81	P = 0.456
I) p-mTOR/mTOR levels (males)	Diet	F (2, 28) = 2.37	P = 0.112
	Metformin	F (1, 28) = 3.88	P = 0.059
	Diet x Metformin	F (2, 28) = 1.65	P = 0.209
J) Total ACC levels (males)	Diet	F (2, 25) = 1.89	P = 0.173
	Metformin	F (1, 25) = 0.13	P = 0.724
	Diet x Metformin	F (2, 25) = 2.21	P = 0.131
K) Phosphorylated-ACC levels (males)	Diet	F (2, 25) = 2.56	P = 0.097
	Metformin	F (1, 25) = 5.21	P = 0.031
	Diet x Metformin	F (2, 25) = 1.66	P = 0.211
L) pACC/ACC levels (males)	Diet	F (2, 25) = 1.16	P = 0.331
	Metformin	F (1, 25) = 0.73	P = 0.400
	Diet x Metformin	F (2, 25) = 1.10	P = 0.349