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CHD1Li Inhibit CSC Stemness in CRC cells. (A) Graphical representation of dose-response inhibition of CSC stemness by the CHD1Li (N = 2). Error bars are the calculated standard error of the mean (SEM) of 2 experiments performed in triplicate. (B) Representative images (25 stitched fields of view on 10x air objective) of 2D SW620-GFP+ colonies treated with CHD1Li for 10 days at 0.25–8 μM and stained with Hoechst dye for imaging. All images were obtained using the Opera Phenix.
