Table 2.
Descriptive statistics of numeric variables (All variables have a total count of 407, FH indicates the fractional helical content)
| Category | Variables | Unit | Unique | Mean | SD | Min | Max |
|---|---|---|---|---|---|---|---|
| AMP Characteristics | Length | a.a. | 20 | 14.39 | 5.8 | 6 | 37 |
| Molecular Weight | g/mol | 65 | 1847.29 | 610.31 | 1044.23 | 4003.84 | |
| Normalized Hydrophobicity | G | 59 | 0.6 | 1.1 | -1.86 | 3.23 | |
| Net Charge | N/A | 11 | 5.86 | 2.12 | 1 | 11 | |
| Isoelectric Point | pH(I) | 18 | 13.63 | 0.96 | 9.93 | 14 | |
| Penetration Depth | Å | 13 | 16.26 | 5.04 | 10 | 30 | |
| Tilt Angle | ° | 46 | 85.89 | 28.86 | 13 | 169 | |
| Disordered Conformation Propensity | FH | 58 | -0.31 | 0.45 | -1.46 | 0.82 | |
| Linear Moment | kgxm/s | 34 | 0.32 | 0.15 | 0 | 0.57 | |
| Amphiphilicity Index | N/A | 60 | 2.14 | 1.24 | 0 | 5.3 | |
| Average Hydrophilicity | G | 48 | 0.03 | 0.45 | -0.98 | 2.16 | |
| Ratio of Hydrophilic Residues/Total | N/A | 32 | 40.13 | 11.46 | 10 | 90 | |
| MIC of AMP | g/mL | 92 | 34.34 | 58.17 | 0.25 | 512 | |
| Antimicrobial Agent Characteristics | Physiological Charge | N/A | 8 | 1.3 | 2.14 | -2 | 5 |
| LogP | N/A | 36 | -1.21 | 3.38 | -8.6 | 4.1 | |
| Water Solubility | mg/mL | 36 | 5.79 | 15.54 | 0.01 | 92.3 | |
| pKa | mol/L | 35 | 7.48 | 4.04 | 2.42 | 12.68 | |
| Molecular Weight | g/mol | 37 | 677.04 | 360.61 | 299.35 | 1449.3 | |
| MIC of Antimicrobial Agent | g/mL | 167 | 66.21 | 161.18 | 0.001 | 2048 | |
| Outcome | FIC Index | N/A | 101 | 0.63 | 0.47 | 0.01 | 1.98 |