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. 2024 Jan 17;6:1. doi: 10.1186/s42490-024-00075-z

Table 2.

Descriptive statistics of numeric variables (All variables have a total count of 407, FH indicates the fractional helical content)

Category Variables Unit Unique Mean SD Min Max
AMP Characteristics Length a.a. 20 14.39 5.8 6 37
Molecular Weight g/mol 65 1847.29 610.31 1044.23 4003.84
Normalized Hydrophobicity ΔG 59 0.6 1.1 -1.86 3.23
Net Charge N/A 11 5.86 2.12 1 11
Isoelectric Point pH(I) 18 13.63 0.96 9.93 14
Penetration Depth Å 13 16.26 5.04 10 30
Tilt Angle ° 46 85.89 28.86 13 169
Disordered Conformation Propensity FH 58 -0.31 0.45 -1.46 0.82
Linear Moment kgxm/s 34 0.32 0.15 0 0.57
Amphiphilicity Index N/A 60 2.14 1.24 0 5.3
Average Hydrophilicity ΔG 48 0.03 0.45 -0.98 2.16
Ratio of Hydrophilic Residues/Total N/A 32 40.13 11.46 10 90
MIC of AMP μg/mL 92 34.34 58.17 0.25 512
Antimicrobial Agent Characteristics Physiological Charge N/A 8 1.3 2.14 -2 5
LogP N/A 36 -1.21 3.38 -8.6 4.1
Water Solubility mg/mL 36 5.79 15.54 0.01 92.3
pKa mol/L 35 7.48 4.04 2.42 12.68
Molecular Weight g/mol 37 677.04 360.61 299.35 1449.3
MIC of Antimicrobial Agent μg/mL 167 66.21 161.18 0.001 2048
Outcome FIC Index N/A 101 0.63 0.47 0.01 1.98