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. 2024 Jan 17;21:23. doi: 10.1186/s12974-023-02969-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Murine intraepidermal Schwann cells in glabrous plantar skin. A, B Representative images of immunostainings of skin sections harvested from hind paw foot pads are displayed (n = 2): Schwann cells were labelled with anti-S100 antibody while intraepidermal nerve fibres were identified with anti-PGP9.5 antibody. The epidermal-dermal border was visualized with anti-Coll IV antibody. Fibres and Schwann cell processes crossing the epidermal-dermal border (dashed line) were counted. Arrows indicate IENF without intraepidermal Schwann cell process, arrowheads intraepidermal Schwann cell processes. Scale bar = 25 µm