Fig. 3.

Intraepidermal Schwann cells in human glabrous skin. Skin biopsies from the index finger at the border between glabrous and hairy skin were immunolabelled. A, B, C Representative images of intraepidermal Schwann cell processes (S100⁺), intraepidermal nerve fibres (IENFs, PGP9.5⁺), Langerhans cells (CD207⁺), and the epidermal-dermal border (collagen IV, Coll IV⁺). Nerve fibres crossing the epidermal-dermal border (dashed lines) were counted as IENF (arrows), S100-positive Schwann cell processes co-localized with them (arrowheads). S100-positive Langerhans cells close to the epidermal-dermal border were excluded (asterisk). Scale bars = 50 µm