Fig. 6.

No apparent lymphocyte infiltration into skin from patients with acute or chronic CRPS. Skin biopsy of the index finger with A T cells (CD3⁺; asterisk) and plasma cells (CD27⁺CD138⁺; arrow and arrowhead). Scale bar = 100 µm. Dashed box indicates B the zoom-in area with T and plasma cells. Scale bar = 30 µm. C, D Densities of T cells in the dermis and epidermis of acute and chronic CRPS patients and HC are depicted. E Plasma cells (CD27⁺CD138⁺) were only detected in 7 samples; outliers were not excluded for plasma cells. Data are shown as median ± interquartile range; Kruskal–Wallis and Dunn's tests; C n_HC = 24, n_acute IL = 18\1, n_acute CL = 19, n_{chronic IL/CL} = 5/6; D n_HC = 21\3, n_acute IL = 19, n_acute CL = 18\1, n_{chronic IL/CL} = 5/6. CL: contralateral; HC: healthy controls; IL: ipsilateral