Table 1.
Summary of demographic and clinical data of healthy control and CRPS study cohorts
| Acute CRPS n = 19 | Chronic CRPS n = 6 | HC n = 25 | |
|---|---|---|---|
| Age (years) | 54 ± 9 | 40 ± 13* | 51 ± 11 |
| Sex (female in %) | 74% | 100% | 80% |
| CRPS type I | 58% (n = 11) | 83% (n = 5) | |
| Initially warm | 63% (n = 12) | 50% (n = 3) | |
| Time since event (months) | 5.2 ± 2.8 | 19.0 ± 4.8 | |
| Time since diagnosis (months) | 2.1 ± 2.5 | 7.3 ± 8.6 | |
| Mean pain (NRS) | 5.3 ± 2.2 | 5.0 ± 2.2 | |
| Max pain (NRS) | 7.4 ± 2.2 | 7.2 ± 3.0 | |
| Allodynia | 37% (n = 7) | 17% (n = 1) | |
| Hyperalgesia | 53% (n = 10) | 66% (n = 4) | |
| Oedema | 79% (n = 15) | 66% (n = 4) | |
| Skin temp (Δ°C) | -0.3 ± 1.4 | 0.5 ± 0.9 | |
| CSS1 | 10.4 ± 1.9 | 10.7 ± 2.1 | |
| NPSI2 | 30.4 ± 22.2 (n = 16) | 35.5 ± 28.1 | 3.2 ± 4.8 (n = 20) |
| STAI-T3 | 45.0 ± 11.0 | 38.7 ± 17.3 | 31.7 ± 7.2 (n = 24) |
| BDI-II4 | 14.6 ± 10.4 (n = 17) | 9.8 ± 9.5 | 3.9 ± 4 (n = 24) |
| DASH5 | 62.4 ± 20.9 (n = 18) | 37.7 ± 23.1 | 3.5 ± 4.1 (n = 23) |
1CRPS severity score, range 0–17
2Neuropathic pain symptom inventory, range 0–100
3State-Trait anxiety inventory trait anxiety subscale, range 20–80
4Beck depression inventory II, range 0–63
5Disability of arm, shoulder and hand, range 0–100. CRPS: complex regional pain syndrome; HC: healthy control; *p < 0.05 compared with acute CRPS group