Figure 3.

(A) Eupenifeldin treatment increases apoptosis in OVCAR3 and OVCAR8. Cells were treated with eupenifeldin (25 nM), paclitaxel (10 nM), or vehicle control (DMSO) for 48 h and stained with annexin-V/PI. Each experiment is represented by three biological replicates, and data are represented using mean ± SEM using one-way ANOVA and Dunnett’s posthoc with p < 0.05. (B) Eupenifeldin activates caspase 3/7 in all three cell lines. Data represented using mean ± SEM using two-way ANOVA and Tukey’s posthoc. Letters represent statistically different groups with a p < 0.05.