Table 1.
Clinical profiles of cutaneous and visceral leishmaniasis patients
| Sl no | Date of collection | Age/sex | Village/district | Site of lesion | Clinical symptoms | Duration | PCR kDNA result | Parasite sp. | Clinical manifestation |
|---|---|---|---|---|---|---|---|---|---|
| 1 | March 1, 2021 | 23 years/M | Kulathupuzha, Kollam | Lateral aspect of the right upper arm, upper chest | Multiple lesions of 1–1.5 cm in diameter with crust formation; 2–2.5 cm in diameter, ulcerated lesion with surrounding erythema and severe itching | > 1 year | Positive | L. donovani | CL |
| 2 | February 22, 2021 | 17 years/F | Kulathupuzha, Kollam | Left and right elbows | 2–2.5 cm in diameter, well-circumscribed ulcerated lesion with surrounding hyperpigmentation; 1.5–2 cm in diameter ill-defined lesion with scaling | > 6 months | Positive | L. donovani | CL |
| 3 | February 22, 2021 | 20 years/F | Kulathupuzha, Kollam | Right cheek | 1.5–2 cm in diameter, nodule with central ulceration and raised margins | > 1 year | Positive | L. donovani | CL |
| 4 | February 22, 2021 | 40 years /F | Kulathupuzha, Kollam | Right upper arm and wrist joint | 1–1.5 cm in diameter, raised lesion with surrounding hypopigmentation; 1–1.5 cm in diameter, nodule with central scab formation with surrounding hyperpigmentation | > 1 year | Positive | L. donovani | CL |
| 5 | March 1, 2021 | 18 years /M | Kulathupuzha, Kollam | Right and left calves | 2–2.5 cm in diameter, ulcerated lesion with surrounding hyperpigmentation; multiple healed hyperpigmented lesions of 1.5–2 cm | > 1 year | Positive | L. donovani | CL |
| 6 | March 1, 2021 | 18 years /F | Kulathupuzha, Kollam | Dorsal aspect of right and left ankle joints | 0.5–1 cm in diameter, crusted lesion with surrounding hyperpigmentation; 0.5 cm in diameter, multiple healed hyperpigmented lesions | > 1 year | Positive | L. donovani | CL |
| 7 | March 23, 2021 | 28 years /M | Kulathupuzha, Kollam | Dorsal aspect of left shoulder | 0.5–1 cm in diameter, nodule | > 1.5 years | Positive | L. donovani | CL |
| 8 | March 15, 2021 | 35 years /M | Kulathupuzha, Kollam | Right pinna, lower elbow of right arm | 0.5–1 cm in diameter, multiple healed lesions with hyperpigmentation | > 1 year | Negative | Negative | – |
| 9 | March 15, 2021 | 5 years /F | Kulathupuzha, Kollam | Lateral aspect of the left buttock | 0.5 cm in diameter, multiple lesions healed with hyperpigmentation | > 4 months | Negative | Negative | – |
| 10 | March 15, 2021 | 40 years /M | Kulathupuzha, Kollam | Umbilical region of the abdomen | 2–2.5 cm in diameter, hyperpigmented papule with diffused margins | > 3 months | Negative | Negative | – |
| 11 | March 15, 2021 | 6 years /F | Kulathupuzha, Kollam | Right knee and calf | 2.5–3 cm in diameter, ulcerated nodular lesion with scaling of surrounding skin | > 3 months | Negative | Negative | – |
| 12 | November 3, 2021 | 42 years /M | Achenkovil, Kollam | Left lumbar and iliac region | Multiple healed pinpoint lesions with surrounding hyperpigmentation | > 2 months | Negative | Negative | – |
| 13 | September 22, 2021 | 6 years /M | Anapantham, Thrissur | Posterior aspect of the left middle arm | 2–2.5 cm in diameter, ulcerated lesion with central scale formation | > 3 months | Negative | Negative | – |
| 14 | September 22, 2021 | 10 years /M | Anapantham, Thrissur | Dorsal aspect of the left ankle region | 0.5–1 cm in diameter, multiple lesions with central scaling | > 6 months | Negative | Negative | – |
| 15 | September 22, 2021 | 8 years /M | Anapantham, Thrissur | Dorsal aspect of the right ankle region | 1.5–2 cm in diameter, central ulcerated lesion with surrounding scale formation | > 3 months | Negative | Negative | – |
| 16 | December 2, 2021 | 13 years /F | Kumaramputhur, Palakkad | – | Hepatospleno-megaly; significant weight loss, pancytopenia, fever | > 2 years | Positive | L. donovani | VL |
| 17 | January 25, 2022 | 60 years /M | Chelakkara, Thrissur | – | Hepatospleno-megaly, significant weight loss, fever, anemia | > 2 years | Positive | L. donovani | VL |
| 18 | February 7, 2022 | 62 years /M | Manalithara, Thrissur | – | Hepatospleno-megaly, weight loss, mild fever | > 5 months | Positive | L. donovani | VL |
CL = cutaneous leishmaniasis; F = female; kDNA = kinetoplast DNA; L. donovani = Leishmania donovani; M = male; PCR = polymerase chain reaction; Sl no = serial number; VL = visceral leishmaniasis.