Table 1.
Comparison of the characteristics of the women with melioidosis with and without genitourinary involvement
| Variable | With data* | Genitourinary tract involved (n = 13) | Genitourinary tract not involved (n = 127) | P |
|---|---|---|---|---|
| Age (years) | 140 | 53 (45–67) | 52 (41–63) | 0.61 |
| First Nations Australian | 140 | 7 (54) | 73 (57) | 1.0 |
| Acute presentation† | 140 | 10 (77) | 117 (92) | 0.10 |
| Wet season presentation | 140 | 7 (54) | 100 (79) | 0.08 |
| Imaging of the genitourinary tract | 112 | 13/112 (12) | 99/127 (88) | 0.07 |
| Urine collected for culture | 117 | 13/117 (11) | 104/127 (89) | 0.13 |
| Diabetes | 140 | 10 (77) | 62 (49) | 0.08 |
| Glycosylated hemoglobin (%) | 67 | 9.8 (9.6–12.6) | 10 (7.5–12.1) | 0.45 |
| Smoker | 128 | 8/13 (62) | 45/115 (39) | 0.14 |
| Hazardous alcohol consumption‡ | 130 | 3/13 (23) | 23/117 (20) | 0.72 |
| Chronic kidney disease | 133 | 2/13 (15) | 14/120 (12) | 0.66 |
| Chronic lung disease | 130 | 4/13 (31) | 24/117 (21) | 0.48 |
| Malignancy | 129 | 1/13 (8) | 11/116 (9) | 1.0 |
| Immunosuppression | 101 | 2/10 (20) | 16/91 (18) | 1.0 |
| No traditional risk factors for the disease§ | 140 | 1 (8) | 22 (17) | 0.69 |
| Bacteremic | 140 | 6 (46) | 78 (61) | 0.38 |
| Pulmonary involvement | 135 | 10/13 (77) | 77/122 (63) | 0.38 |
| Central nervous system involvement | 132 | 1 (8) | 4/119 (3) | 0.41 |
| Skin or soft tissue infection | 132 | 2 (15) | 24/119 (20) | 1.0 |
| Musculoskeletal | 132 | 5/13 (38) | 12/119 (10) | 0.01 |
| Any abscess | 121 | 7/12 (58) | 44/109 (40) | 0.36 |
| Septic shock | 125 | 2/12 (17) | 27/113 (24) | 0.73 |
| Intensive care unit admission | 140 | 4 (31) | 32 (25) | 0.74 |
| Died | 140 | 1 (8) | 16 (13) | 1.0 |
Numbers are the median (interquartile range) or absolute numbers (%).
*
Data were collected retrospectively prior to October 2016, resulting in incomplete data prior to this date.
†
Presentation within 2 months of symptom onset.3
‡
As defined in Australian national guidelines.7
§
Traditional risk factors: diabetes mellitus, hazardous alcohol consumption, chronic lung disease, chronic kidney disease, immunosuppression, and active malignancy. Note that retrospective data collection of the 49 cases prior to October 2016 may have underestimated the prevalence of these risk factors prior to that date.